PD Dr.
Steven R. Talbot

Data Scientist | Biochemist | Consultant

About Me

I am a data scientist (and biochemist), and leader of the Preclinical Data Science group at the Institute for Laboratory Animal Science at Hannover Medical School (MHH), where I specialise in the intersection of artificial intelligence, statistics, and translational laboratory animal/veterinary research.

My research focuses on developing data-science-driven solutions for quantitative severity assessment in animal research. A major achievement has been the RELSA (Relative Severity Assessment) score, which has also been adapted for pediatric care as the Patient Vital Score (PVS). I apply AI and statistical methods to support regulatory processes, experimental design, and the 3Rs principles in preclinical research.

Research Interests

  • Severity Assessment: Multidimensional scoring algorithms (e.g., RELSA) for objective burden quantification
  • AI in Regulatory Science: LLM-assisted evaluation and optimization of animal experiment applications
  • Clinical Translation: From animal welfare scores to human ICU monitoring (Patient Vital Status)
  • Experimental Design: Bayesian sample size planning and multi-center reproducibility validation
  • 3Rs & Alternative Methods: Data-driven reduction strategies and organoid model validation

Current Position

Group Leader, Preclinical Data Science Institute of Laboratory Animal Science Hannover Medical School (MHH) Hannover, Germany

Affiliations

  • Co-founder, GMDS Working Group “AI in Research”
  • Member, Gesellschaft für Biochemie und Molekularbiologie (GBM)
  • Member, Deutsche Gesellschaft für Gentheratpie (DG-GT)
  • Vivid Contributor to the 3R-Competence Network NRW
  • PI, R2N Research Network
  • PI, FOR2591

Education

Habilitation in Data Science (PD) | Hannover Medical School (GER) | 2025

Dr. rer. nat. | Leibniz University Hannover (GER) | 2009

Diploma in Biochemistry | Leibniz University Hannover (GER) | 2006

Contact

Feel free to reach out if you’re interested in collaboration or have questions about my work.