Baskaya, Ferhan MD; Lemainque, Teresa PhD; Klinkhammer, Barbara
PhD; Koletnik, Susanne BSc; von Stillfried, Saskia MD; Talbot,
Steven R. PhD; Boor, Peter MD; Schulz, Volkmar PhD; Lederle,
Wiltrud PhD; Kiessling, Fabian MD. Pathophysiologic Mapping of Chronic
Liver Diseases With Longitudinal Multiparametric MRI in Animal Models.
Investigative Radiology ():10.1097/RLI.0000000000001075, April 10,
2024.
Knorr, Ivonne Jeanette, Leonie Tix, Wenjia Liu, Steven R.
Talbot, Mareike Schulz, Laura Bell, Babette Kögel, Rene Tolba,
and Lisa Ernst. 2024. “Refinement in Post-Operative Care for Orthopaedic
Models: Implementing a Sheep Walking Cast (SWC) for Effective Tibial
Fracture Management”. Biomedicines 12, no. 2: 343. https://doi.org/10.3390/biomedicines12020343.
Becker L, Mallien AS, Pfeiffer N, Brandwein C, Talbot
SR, et al. (2023) Evidence-based severity assessment of the
forced swim test in the rat. PLOS ONE 18(10): e0292816.
https://doi.org/10.1371/journal.pone.0292816.
Keubler, L. M., Talbot, S. R., Bleich, A., &
Boyle, E. C. (2023). Systematic review and meta-analysis of the effect
of fecal microbiota transplantation on behavior in animals.
Neuroscience & Biobehavioral Reviews,
105316.
Braun T, Pruene A, Darguzyte M, vom Stein AF, Nguyen P-H, Wagner
DL, Kath J, Roig-Merino A, Heuser M, Riehm LL, Schneider A, Awerkiew S,
Talbot SR, Bleich A, Figueiredo C, Bornhäuser M and
Stripecke R (2023) Non-viral TRAC-knocked-in CD19KICAR-T and
gp350KICAR-T cells tested against Burkitt lymphomas with type 1 or 2 EBV
infection: In vivo cellular dynamics and potency. Front.
Immunol. 14:1086433. doi: https://doi.org/10.3389/fimmu.2023.1086433.
Tix L, Ernst L, Bungardt B, Talbot SR, Hilken G, Tolba RH (2023)
Establishment of the body condition score for adult female Xenopus
laevis. PLoS ONE 18(4): e0280000. https://doi.org/10.1371/journal.pone.0280000.
Daniel Segelcke, Steven R. Talbot, Rupert Palme,
Carmen La Porta, Esther Pogatzki-Zahn, André Bleich & Anke
Tappe-Theodor. Experimenter familiarization is a crucial prerequisite
for assessing behavioral outcomes and reduces stress in mice not only
under chronic pain conditions, Sci Rep 13, 2289 (2023).
https://doi.org/10.1038/s41598-023-29052-7.
Teresa Schmidt, Sebastian Meller, Steven R.
Talbot, Rowena Mary Anne Packer, Holger Andreas Volk. Urinary
neurotransmitter analysis and canine behavior assessment, Front.
Vet. Sci., (2023). 10:1124231. doi: https://doi.org/10.3389/fvets.2023.1124231.
Anna Lieske, Eric Agyeman-Duah, Anton Selich, Nicole Dörpmund,
Steven R. Talbot, Axel Schambach & Tobias Maetzig.
A pro B cell population forms the apex of the leukemic hierarchy in
Hoxa9/Meis1-dependent AML. Leukemia (2022). https://doi.org/10.1038/s41375-022-01775-y.
Pfeffer, T. J., Mueller, J. H., Haebel, L., Erschow, S., Yalman,
K. C., Talbot, S. R., Koenig, T., Berliner, D., Zwadlo,
C., Scherr, M., Hilfiker-Kleiner, D., Bauersachs, J., and Ricke-Hoch, M.
(2022) Cabergoline treatment promotes myocardial recovery in peripartum
cardiomyopathy, ESC Heart Failure, doi: https://doi.org/10.1002/ehf2.14210
Bufe S, Zimmermann A, Ravens S, Prinz I, Buitrago-Molina L, E,
Geffers R, Woller N, Kühnel F, Talbot S, R, Noyan F,
Manns M, P, Wedemeyer H, Hardtke-Wolenski M, Jaeckel E, Davalos-Misslitz
A, C; PD-1/CTLA-4 blockade leads to expansion of CD8+PD-1int TILs and
results in tumor remission in experimental liver cancer. Liver
Cancer 2022. doi: 10.1159/000526899.
Alice Rovai, BoMee Chung, Qingluan Hu, Sebastian Hook, Qinggong
Yuan, Tibor Kempf, Florian Schmidt, Dirk Grimm, Steven R.
Talbot, Lars Steinbrück, Jasper Götting, Jens Bohne, Simon A.
Krooss & Michael Ott. In vivo adenine base editing reverts C282Y and
improves iron metabolism in hemochromatosis mice. Nat
Commun 13, 5215 (2022). https://doi.org/10.1038/s41467-022-32906-9.
Meumann, N., Cabanes-Creus, M., Ertelt, M., Navarro, R.G.,
Lucifora, J., Yuan, Q., Nien-Huber, K., Abdelrahman, A., Vu, X.-K.,
Zhang, L., Franke, A.-C., Schmithals, C., Piiper, A., Vogt, A.,
Gonzalez-Carmona, M., Frueh, J.T., Ullrich, E., Meuleman, P.,
Talbot, S.R., Odenthal, M., Ott, M., Seifried, E.,
Schoeder, C.T., Schwäble, J., Lisowski, L. and Büning, H. (2022), Novel
Adeno-Associated Virus (AAV) Serotype 2 Capsid Variants for Improved
Liver-Directed Gene Therapy. Hepatology. https://doi.org/10.1002/hep.32733.
Schmidt T, Meller S, Talbot SR, Berk BA, Law TH,
Hobbs SL, Meyerhoff N, Packer RMA and Volk HA (2022) Urinary
Neurotransmitter Patterns Are Altered in Canine Epilepsy. Front.
Vet. Sci. 9:893013. doi: 10.3389/fvets.2022.893013
Nicole Brüder, Jan T Kielstein, Luca-Marie Heinze, Catherina
Lück, Victoria Panagiota, Elke Dammann, Sophia Köhler, Steven
Talbot, Michael Stadler, Michael Heuser, Arnold Ganser,
Matthias Eder, Gernot Beutel, MO343: Deep Analysis of The AKI—CKD in
Allogeneic Stem Cell Transplantation—A Big Data Approach,
Nephrology Dialysis Transplantation, Volume 37, Issue
Supplement_3, May 2022, gfac068.053, https://doi.org/10.1093/ndt/gfac068.053
Katharina Ruskowski, Holger Neb, Steven R
Talbot, Suma Choorapoikayil, Elisabeth H Adam, Andreas von
Knethen, Kai Zacharowski, and Ulrike Heinicke. Persistently Elevated
Plasma Levels of RIPK3, MLKL, HMGB1, and RIPK1 in COVID-19 ICU Patients.
American Journal of Respiratory Cell and Molecular
Biology. 2022. doi: https://doi.org/10.1165/rcmb.2022-0039LE.
Ann-Kristin Riedesel, Annika Bach-Hagemann, Arif Abdulbaki,
Steven R Talbot, René Tolba, Kerstin Schwabe, Ute
Lindauer. Burrowing behaviour of rats: Strain differences and
applicability as well-being parameter after intracranial surgery.
Laboratory Animals. February 2022. doi:https://doi.org/10.1177/00236772211072977.
Buchecker V, Koska I, Pace C, Talbot S, R, Palme
R, Bleich A, Potschka H: Toward evidence-based severity assessment in
mouse models with repeated seizures: (II.) Impact of surgery and
intrahippocampal kainate. Eur Surg Res 2022. doi: https://doi.org/10.1159/000522156.
Meumann N, Schmithals C, Elenschneider L, Hansen T, Balakrishnan
A, Hu Q, Hook S, Schmitz J, Bräsen JH, Franke A-C, Olarewaju O,
Brandenberger C, Talbot SR, Fangmann J, Hacker UT,
Odenthal M, Ott M, Piiper A, Büning H. Hepatocellular Carcinoma Is a
Natural Target for Adeno-Associated Virus (AAV) 2 Vectors.
Cancers. 2022; 14(2):427. https://doi.org/10.3390/cancers14020427
Weegh N, Zentrich E, Zechner D, Struve B, Wassermann L,
Talbot SR, et al. (2021) Voluntary wheel running
behaviour as a tool to assess the severity in a mouse pancreatic cancer
model. PLoS ONE 16(12): e0261662. https://doi.org/10.1371/journal.pone.0261662
Durst M, Graf TR, Graf R, Kron M, Arras M, Zechner D, Palme R,
Talbot SR and Jirkof P (2021) Analysis of Pain and
Analgesia Protocols in Acute Cerulein-Induced Pancreatitis in Male
C57BL/6 Mice. Front. Physiol. 12:744638. doi: https://doi.org/10.3389/fphys.2021.744638.
Min Yang, Zengkai Pan, Kezhi Huang, Guntram Büsche, Hongyun Liu,
Gudrun Göhring, Regina Rumpel, Oliver Dittrich-Breiholz, Steven
Talbot, Michaela Scherr, Anuhar Chaturvedi, Matthias Eder,
Julia Skokowa, Jianfeng Zhou, Karl Welte, Nils von Neuhoff, Ligen Liu,
Arnold Ganser & Zhixiong Li. A unique role of p53 haploinsufficiency
or loss in the development of acute myeloid leukemia with FLT3-ITD
mutation. Leukemia (2021). https://doi.org/10.1038/s41375-021-01452-6.
Zentrich E, Talbot SR, Bleich A and Häger C
(2021) Automated Home-Cage Monitoring During Acute Experimental Colitis
in Mice. Front. Neurosci.. 2021; 15:760606. https://doi.org/10.3389/fnins.2021.760606.
Kumar S, Koenig J, Schneider A, Wermeling F, Boddul S, Theobald
SJ, Vollmer M, Kloos D, Lachmann N, Klawonn F, Lienenklaus S,
Talbot SR, Bleich A, Wenzel N, von Kaisenberg C, Keck
J, Stripecke R. In Vivo Lentiviral Gene Delivery of HLA-DR and
Vaccination of Humanized Mice for Improving the Human T and B Cell
Immune Reconstitution. Biomedicines. 2021; 9(8):961. https://doi.org/10.3390/biomedicines9080961
Zieglowski L, Kümmecke AM, Ernst L, Palme R, Weiskirchen R,
Talbot SR, et al. (2021) Assessing the severity of
laparotomy and partial hepatectomy in male rats—A multimodal approach.
PLoS ONE 16(8): e0255175. https://doi.org/10.1371/journal.pone.0255175.
Safia O, Talbot SR, Kuebler S and Mall JW.
Another Brick in the Wall of an Ongoing Discussion–Reduction of
Anastomotic Leaks after Colorectal Resection by Preoperative Mechanical
Bowel Preparation in Combination with Oral and Parenteral Antibiotics?–A
Clinical Retrospective Single Center Study. Austin J ClinCase
Rep., 2021; 8(5): 1211.
Mattea S. Durst, Margarete Arras, Rupert Palme, Steven R.
Talbot & Paulin Jirkof. Lidocaine and bupivacaine as part
of multimodal pain management in a C57BL/6J laparotomy mouse model.
Sci Rep 11, 10918 (2021). https://doi.org/10.1038/s41598-021-90331-2.
Julia K. Bialek-Waldmann, (…), Steven R. Talbot,
Andre Bleich, Loukia M. Spineli, (…), Renata Stripecke; (2021). Induced
Dendritic Cells Co-expressing GM-CSF/ IFN-α/ tWT1 Priming T and B cells
and Automated Manufacturing to Boost GvL. Molecular
Therapy. DOI: 10.1016/j.omtm.2021.04.004.
S. Van der Mierden, L. M. Spineli, S. R. Talbot,
Ch. Yiannakou, E. Zentrich, N. Weegh, B. Struve, T. Zur Brügge, A.
Bleich, C. Leenaars; (2021). Extracting data from graphs: a case‐study
on animal research with implications for meta‐analyses. Research
Synthesis Methods. https://doi.org/10.1002/jrsm.1481.
Lena Boldt, Ines Koska, R. Maarten van Dijk, Steven R.
Talbot, Nina Miljanovic, Rupert Palme, André Bleich, Heidrun
Potschka; (2021). Toward evidence-based severity assessment in mouse
models with repeated seizures: I. Electrical kindling. Epilepsy
& Behavior 115. https://doi.org/10.1016/j.yebeh.2020.107689.
Hanna Kirchhoff, Uemran Karsli, Caroline Schoenherr, Karin
Battmer, Sergej Erschow, Steven Roger Talbot, Doris
Steinemann, Michael Heuser, Olaf Heidenreich, Denise Hilfiker-Kleiner,
Arnold Ganser, Matthias Eder, Michaela Scherr; (2020). Venetoclax and
dexamethasone synergize with inotuzumab-ozogamicin induced DNA damage
signaling in B-lineage ALL. Blood blood.2020008544. https://doi.org/10.1182/blood.2020008544.
Wassermann Laura, Helgers Simeon O. A., Riedesel Ann-Kristin,
Talbot Steven R., Bleich André, Schwabe Kerstin, Häger
Christine; (2020). Monitoring of Heart Rate and Activity Using Telemetry
Allows Grading of Experimental Procedures Used in Neuroscientific Rat
Models. Frontiers in Neuroscience, 14:587760. https://www.frontiersin.org/articles/10.3389/fnins.2020.587760/full.
Qinghai Tan, Gabriella di Stefano, Xinjie Tan, Xiu Renjie,
Dorothee Römermann, Steven R. Talbot, Ursula E.
Seidler; (2020). Inhibition of Na+/H+ exchanger isoform 3 improves gut
fluidity and alkalinity in cystic fibrosis transmembrane conductance
regulator‐deficient and F508del mutant mice. British Journal of
Pharmacology. https://doi.org/10.1111/bph.15323.
Guanglin Tang, Nico Seume, Christine Häger, Simone Kumstel,
Kerstin Abshagen, André Bleich, Brigitte Vollmar, Steven R.
Talbot, Xianbin Zhang & Dietmar Zechner; (2020). Comparing
distress of mouse models for liver damage. Sci Rep 10, 19814.
https://doi.org/10.1038/s41598-020-76391-w.
Veronica Begni, Alice Sanson, Natascha Pfeiffer, Christiane
Brandwein, Dragos Inta, Steven R. Talbot, Marco Andrea
Riva, Peter Gass, Anne Stephanie Mallien; (2020). Social isolation in
rats: Effects on animal welfare and molecular markers for
neuroplasticity. PLOS ONE, https://doi.org/10.1371/journal.pone.0240439.
van der Mierden, S., Leenaars, C. H. C., Boyle, E. C., Ripoli, F.
L., Gass, P., Durst, M., Goerlich-Jansson, V. C., Jirkof, P., Keubler,
L. M., Talbot, S. R., Habedank, A., Lewejohann, L.,
Tolba, R. H. and Bleich, A. (2020) “Measuring endogenous corticosterone
in laboratory mice - a mapping review, meta-analysis, and open source
database”, ALTEX - Alternatives to animal experimentation, https://doi.org/10.14573/altex.2004221.
Lisa Ernst, Leonie Zieglowski, Mareike Schulz, Michaela Moss,
Marco Meyer, Ralf Weiskirchen, Rupert Palme, Melanie Hamann,
Steven R. Talbot & René H. Tolba. Severity
assessment in mice subjected to carbon tetrachloride. Sci Rep
10, 15790 (2020). https://doi.org/10.1038/s41598-020-72801-1.
Zieglowski, L., Kümmecke, A., Ernst, L., Schulz, M.,
Talbot, S. R., Palme, R., Czaplik M., Tolba, R. H.
(2020). Severity assessment using three common behavioral or locomotor
tests after laparotomy in rats: a pilot study. Laboratory
Animals. https://doi.org/10.1177/0023677220911680.
Simone Kumstel, Edgar H. U. Wendt, Johanna Eichberg,
Steven R. Talbot, Christine Haeger, Xianbin Zhang,
Ahmed Abdelrahman, Maria Schoenrogge, Rupert Palme, André Bleich,
Brigitte Vollmar, Dietmar Zechner. (2020). Grading animal distress and
side effects of therapies. Annals of the New York Academy of
Sciences. https://doi.org/10.1111/nyas.14338.
Mallien, A. S., Häger, C., Palme, R., Talbot, S.
R., Vogt, M. A., Pfeiffer, N., … Gass, P. (2020). Systematic
analysis of severity in a widely used cognitive depression model for
mice. Laboratory Animals, 54(1), 40–49. https://doi.org/10.1177/0023677219874831.
Xianbin Zhang, Simone Kumstel, Guanglin Tang, Steven
R.Talbot, Nico Seume, Kerstin Abshagen, Brigitte Vollmar and
Dietmar Zechner (2019) A rational approach of early humane endpoint
determination in a murine model for cholestasis. ALTEX. DOI: https://doi.org/10.14573/altex.1909111.
Leonardo Silva de Araujo, Marcelo Ribeiro-Alves, Thyago
Leal-Calvo, Janaína Leung, Verónica Durán, Mohamed Samir, Steven
Talbot, Aravind Tallam, Fernanda Carvalho de Queiroz Mello,
Robert Geffers, Maria Helena Féres Saad, Frank Pesslera (2019)
Reprogramming of Small Noncoding RNA Populations in Peripheral Blood
Reveals Host Biomarkers for Latent and Active Mycobacterium tuberculosis
Infection. mBio. DOI: https://mbio.asm.org/content/10/6/e01037-19.
Lydia M Keubler, Nils Hoppe, Heidrun Potschka, Steven R
Talbot, Brigitte Vollmar, Dietmar Zechner, Christine Häger, and
André Bleich (2019) Where are we heading? Challenges in evidence-based
severity assessment. Laboratory Animals. DOI: https://doi.org/10.1177/0023677219877216.
Paulin Jirkof, Ahmed Abdelrahman, André Bleich, Mattea Durst,
Lydia Keubler, Heidrun Potschka, Birgitta Struve, Steven R
Talbot, Brigitte Vollmar, Dietmar Zechner, Christine Häger
(2019) A safe bet? Inter-laboratory variability in behaviour-based
severity assessment. Laboratory Animals. DOI: https://doi.org/10.1177/0023677219881481.
Lisa Ernst, Marcin Kopaczka, Mareike Schulz, Steven R
Talbot, Birgitta Struve, Christine Häger, André Bleich, Mattea
Durst, Paulin Jirkof, Margarete Arras, Roelof Maarten van Dijk, Nina
Miljanovic, Heidrun Potschka, Dorit Merhof, Rene H Tolba (2019)
Semi-automated generation of pictures for the Mouse Grimace Scale: A
multi-laboratory analysis (Part 2). Laboratory Animals. DOI: https://journals.sagepub.com/doi/full/10.1177/0023677219881664.
Lisa Ernst, Marcin Kopaczka, Mareike Schulz, Steven R
Talbot, L Zieglowski, M Meyer, S Bruch, Dorit Merhof, Rene H
Tolba (2019) Improvement of the Mouse Grimace Scale set-up for
implementing a semi-automated Mouse Grimace Scale scoring (Part 1).
Laboratory Animals. DOI: https://doi.org/10.1177/0023677219881655.
Cathalijn H.C. Leenaars, Stevie van der Mierden, Mattea Durst,
Vivian C Goerlich-Jansson, Florenza Lüder Ripoli, Lydia M Keubler,
Steven R Talbot, Erin Boyle, Anne Habedank, Paulin
Jirkof, Lars Lewejohann, Peter Gass, René Tolba, André Bleich (2019)
Measurement of corticosterone in mice: a protocol for a mapping review.
Laboratory Animals. DOI: https://doi.org/10.1177/0023677219868499
Stephanie Buchheister, Florian Roegener, Nils-Holger Zschemisch,
Steven R. Talbot, Henrik Christensen, André Bleich
(2019) One for two: A novel and highly sensitive virulence factor-based
quantitative polymerase chain reaction assay for the simultaneous
detection of Rodentibacter pneumotropicus and Rodentibacter heylii in
environmental sample material. Laboratory Animals. https://doi.org/10.1177/0023677219853600.
Häger C, Keubler LM, Talbot SR, Biernot S, Weegh
N, et al. (2018) Running in the wheel: Defining individual severity
levels in mice. PLOS Biology 16(10): e2006159. https://doi.org/10.1371/journal.pbio.2006159.
Prajeeth CK, Dittrich-Breiholz O, Talbot SR,
Robert PA, Huehn J and Stangel M (2018) IFN-γ Producing Th1 Cells Induce
Different Transcriptional Profiles in Microglia and Astrocytes.
Front. Cell. Neurosci. 12:352. doi:
10.3389/fncel.2018.00352.
Skuljec J, Jirmo AC, Habener A, Talbot SR, Pul
R, Grychtol R, Aydin M, Kleinschnitz C, Happle C and Hansen G (2018)
Absence of Regulatory T Cells Causes Phenotypic and Functional Switch in
Murine Peritoneal Macrophages. Front. Immunol. 9:2458. doi:
10.3389/fimmu.2018.02458.
Felix F. Adams, Dirk Heckl, Thomas Hoffmann, Steven R.
Talbot, Arnold Kloos, Felicitas Thol, Michael Heuser, Johannes
Zuber, Axel Schambach, Adrian Schwarzer; An optimized lentiviral vector
system for conditional RNAi and efficient cloning of microRNA embedded
short hairpin RNA libraries, Biomaterials, 139 (2017) 102e115.
DOI: 10.1016/j.biomaterials.2017.05.032.
C. Häger, S. Biernot, M. Buettner, S. Glage, L.M. Keubler, N.
Held, E.M. Bleich, K. Otto, C.W. Müller, S. Decker, S.R.
Talbot and A. Bleich; The Sheep Grimace Scale as an indicator
of post-operative distress and pain in laboratory sheep,
PONE-D-16-36391R2.
Tonio Oumeraci, Vanessa Jensen, Steven R.
Talbot, Winfried Hofmann, Markus Kostrzewa, Brigitte
Schlegelberger, Nils von Neuhoff, Susanne Häußler; Comprehensive
MALDI-TOF biotyping of the non-redundant Harvard Pseudomonas aeruginosa
PA14 transposon insertion mutant library, PLOS ONE, 2014, DOI:
10.1371/journal.pone.0117144.
G. Sartorius, Steven R. Talbot; Classification
of inactivated pathogens using multivariate adaptive embedding,
Fortschritt-Berichte VDI (Autonomous Systems, Proceedings),
2013, Reihe 10-827.